Two girls die in hospital days after Sydenham house fire [Video]

Five-year-old Izabelle, her 21-month-old sister and their three-year-old step-brother, Kalais, were rescued from the burning home in Sydenham about 9.30pm on Sunday.

The girls died in hospital this morning surrounded by family and the boy remained in a critical condition, police said.

Five-year-old Izabelle, three-year-old Kalais and their 21-month-old sister were rescued from the burning home in Sydenham about 9.30pm on Sunday. (Nine)

Detectives from the Arson and Explosives Squad are investigating.

They are working to determine what may have caused the fire and who was in the home at the time and just before to the blaze.

Kalais’ father, Jayde Petalas, who doesn’t live at the house, last week said he was heartbroken after receiving the call from police about the fire.

“They were the best little kids. They would have been petrified,” he said.

“I hope they didn’t feel anything to be honest. Obviously they would have, but I just tell myself they didn’t.”

Police understand …